| Ships Tavern & Kings Head | Arcadia Road, Plymouth, Devon, PL9 8EG |
| Sir Joshua Reynolds | 25 The Ridgeway, Plympton, Plymouth, Devon, PL7 2AW |
| SizzALL | 15 Derry Cross, Plymouth, Devon, PL1 2SW |
| Skinny Niks | 8 Union Street, Plymouth, Devon, PL1 2SR |
| Skiving Scholar | 1 Tavistock Place, North Hill, Plymouth, Devon, PL4 8AU |
| Sloopys | Unit 8, Bretonside Bus Station, Plymouth, Devon, PL4 0BG |
| Sloopy's | 7-9 Exeter Street, Plymouth, Devon, PL4 0AQ |
| Slots of fun | 80 Ebrington Street, Plymouth, Devon, PL4 9AQ |
| Slots of Fun | 82 Ebrington Street, Plymouth, Devon, PL4 9AQ |
| Slug & Lettuce | 17-19 Princess Street, Plymouth, Devon, PL1 2EU |
